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Friday, November 13, 2020 | History

1 edition of RNA interference and viruses found in the catalog.

RNA interference and viruses

Miguel Angel MartГ­nez

RNA interference and viruses

current innovations and future trends

by Miguel Angel MartГ­nez

  • 377 Want to read
  • 34 Currently reading

Published by Caister Academic Press in Norfolk, UK .
Written in English


Edition Notes

Includes bibliographical references and index.

Statementedited by Miguel Angel Martínez
Classifications
LC ClassificationsQR395 .R573 2010
The Physical Object
Paginationvii, 252 p. :
Number of Pages252
ID Numbers
Open LibraryOL24385410M
ISBN 101904455565
ISBN 109781904455561
LC Control Number2010286581
OCLC/WorldCa426816276

RNA silencing, including RNA interference, is a novel method of gene regulation and one of the potent host-defense mechanisms against the viruses. In the course of evolution, the viruses have encoded proteins with the potential to suppress the host RNA silencing mechanism as a counterdefense by:


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RNA interference and viruses by Miguel Angel MartГ­nez Download PDF EPUB FB2

In this book, expert RNAi specialists from around the world have teamed up to produce a timely and thought-provoking review of the area. The two central themes are the latest findings on RNAi-virus interactions and the current progress in the development of RNAi-based antiviral therapeutics.

A number of chapters explain general concepts concerned with the role of RNAi. RNA interference (RNAi) is a mechanism for sequence-specific gene silencing triggered by double-stranded (ds) RNA. RNAi constitutes an effective antiviral defense mechanism in many organisms. Accordingly, viruses interact with the RNAi pathway at different levels.

As a counter-defense, viruses have evolved suppressors of the RNAi pathway. RNA Interference and Viruses: Current Innovations and Future Trends [Martà ­nez, Miguel Angel] on *FREE* shipping on qualifying offers.

RNA Interference and Viruses: Current Innovations and Future Trends. RNA mediated silencing technology has now become the RNA interference and viruses book of choice for induction of virus resistance in plants.

A significant feature of this technology is the presence of double-stranded RNA (dsRNA), which is not only the product of RNA silencing but also the potent triggers of RNA interference (RNAi).Cited by: 2.

Susan Payne, in Viruses, Abstract. RNA viruses replicate their genomes using virally encoded RNA-dependent RNA polymerase (RdRp). The RNA genome is the template for synthesis of additional RNA strands. During replication of RNA viruses, there are at least three types of RNA that must be synthesized: the genome, a copy of the genome (copy genome).

Get this from a library. RNA interference and viruses: current innovations and future trends. [Miguel Angel Martínez;] -- "Since its discovery inRNA interference (RNAi) has heralded the advent of novel tools for biological research and drug discovery.

This exciting new technology is emerging as a powerful. RNA viruses, which is attributed to the lack of proofreading activity of viral RNA-dependent RNA polymerase. Thus, in the recent years, research focusing on understanding the molecular pathogenesis of RNA viruses have been very active and made tremendous advances.

In this book, we have organized 27 chapters written by highly respective virologists5/5(1). RNA interference (RNAi) was shown over 18 years ago to be a mechanism by which arbovirus replication and transmission could be controlled in arthropod vectors.

During the intervening period, research on RNAi has defined many of the components and mechanisms of this antiviral pathway in arthropods, yet a number of unexplored questions remain. RNAi refers to RNA Cited by: Since its discovery inRNA interference (RNAi) has heralded the advent of novel tools for biological research and drug discovery.

This exciting new technology is emerging as a powerful modality for battling some of the most notoriously challenging viral clinical targets such as hepatitis C virus (HCV) and human immunodeficiency virus (HIV).

RNA interference (RNAi), an evolutionarily conserved mechanism triggered by double-stranded RNA (dsRNA), causes gene silencing in a sequence-specific manner. RNAi evolved naturally to mediate protection from both endogenous and exogenous pathogenic nucleic acids and to modulate gene expression. Multiple technological advancements and precision in gene Author: Devi Singh, Sarika Chaudhary, Rajendra Kumar, Kamiya Mehla Preeti Sirohi, Anil Sirohi, Shashi Kumar.

RNA Interference (RNAi) Introduction. RNA interference or Post-Transcriptional Gene Silencing is a conserved biological response to double-stranded RNA that mediates resistance to both endogenous parasitic and exogenous pathogenic nucleic acids, and regulates the expression of protein-coding natural mechanism for sequence-specific gene silencing promises.

RNA interference and viruses book   Usually you shouldn't use a book to study RNA biology but if you really wanted one, the typical one gathering dust on everyone's bookshelf is The RNA World, Third Edition.

However, since that book was published in which is basically the stone. RNA interference (RNAi) is a novel and effective way to cure a wide range of viruses. We constructed three short hairpin RNA (shRNA)-expressing plasmids (shR-N, shR-N, and shR-N) directed against nucleocapsid (N) and determined their antiviral activities in intestine epithelial cells infected with a classical CV strain and LNCT2.

Systematic Veterinary Virology. This note explains the following topics: structure, classification, repliation and viral interference, Group V viruses, Negative sense single stranded RNA viruses, Morbilli virus, Orthomyxo viruses, Equine flu, nature of the virus, disease and its pathogenesis, diagnosis and various lab tests, vaccines, Zoonotic potential, Impacts of swine flu, Negative.

The book ‘RNA Interference and Viruses: Current Innovations and Future Trends’, edited by Miguel Angel Martinez, is a timely and well-compiled book, authored by several distinguished sci-entists who have made significant contributions to this impor-tant area of emerging research.

The book consists of 11 chapters. A virus is a submicroscopic infectious agent that replicates only inside the living cells of an s can infect all types of life forms, from animals and plants to microorganisms, including bacteria and archaea. Since Dmitri Ivanovsky's article describing a non-bacterial pathogen infecting tobacco plants, and the discovery of the tobacco mosaic virus by Martinus (unranked): Virus.

RNA interference is a featured article; it (or a previous version of it) has been identified as one of the best articles produced by the Wikipedia so, if you can update or improve it, please do so.

This article appeared on Wikipedia's Main Page as Today's featured article on Novem   RNA interference (RNAi) is a mechanism that inhibits gene expression at the stage of translation or by hindering the transcription of specific genes.

RNAi targ Slideshare uses cookies to improve functionality and performance, and to provide you with relevant advertising. PDF | RNA mediated silencing technology has now become the tool of choice for induction of virus resistance in plants. A significant feature of this | Find, read and cite all the research you.

RNA Interference. View the animation below, then complete the quiz to test your knowledge of the concept. Antisense mRNA can be produced during the life cycle of all viruses.

A) True: B) False: To learn more about the book this website supports, please visit its Information Center. McGraw-Hill Higher Education. I Googled and read about this so now I know what siRNA and RISC and microRNA are.

But the next thing my book says is “the source of these complementary double stranded RNA sequence [obviously my textbook means siRNA] may be viruses and transposable elements.” What does this mean.

Do transposons make siRNA. RNA Interference in Insect Vectors for Plant Viruses Article (PDF Available) in Viruses 8(12) December with Reads How we measure 'reads'. RNA Interference (RNAi) is one of the most important technological breakthroughs in modern biology, allowing us to directly observe the effects of the loss of function of specific genes in mammalian systems.

In the early s, a number of scientists observed independently that RNA inhibited protein expression in plants and fungi (Figure 1).

Defenses against these viruses may involve RNA interference from repetitive DNA sequences that are related to the genes of the viruses. The second single stranded DNA virus infecting Archaea is Aeropyrum coil-shaped virus (ACV). The genome is circular and w nucleotides is currently the largest known ssDNA genome.

RNA Interference Technology: From Basic Science to Drug Development is primarily intended for readers in the molecular cell biology and genomics fields but may be useful in more advanced graduate level courses. Much of the text should be of interest to those in applied sciences such as molecular medicine, genome science, and : $ Get this from a library.

RNA viruses: host gene responses to infections. [Decheng Yang;] -- This is the first comprehensive book on human/animal gene responses to RNA viral infections, including prevalent, emerging and re-emerging RNA viruses such as.

RNA, complex compound of high molecular weight that functions in cellular protein synthesis and replaces DNA as a carrier of genetic codes in some viruses. RNA consists of ribose nucleotides and the nitrogenous bases adenine, guanine, cytosine, and uracil.

Learn about the structure, types, and functions of RNA. How RNAi Works. The term RNA interference (RNAi) was coined to describe a cellular mechanism that use the gene's own DNA sequence of gene to turn it off, a process that researchers call a wide variety of organisms, including animals, plants, and fungi, RNAi is triggered by double-stranded RNA (dsRNA).

During RNAi, long dsRNA is cut or. RNA is typically single stranded and is made of ribonucleotides that are linked by phosphodiester bonds.

A ribonucleotide in the RNA chain contains ribose (the pentose sugar), one of the four nitrogenous bases (A, U, G, and C), and a phosphate group.

The subtle structural difference between the sugars gives DNA added stability, making DNA more. RNA interference (RNAi) is a process in living adjusts (moderates) the activity of their molecules are a key to geneAndrew Fire and Craig Mello shared the Nobel Prize in Physiology or Medicine for their work on RNA interference in the nematode worm Caenorhabditis elegans, published in Two types of small RNA molecules –.

RNA interference (RNAi) is a natural mechanism within the cell used to silence the expression of certain genes. Small RNA molecules play essential roles in regulating gene expression by RNA interference.

There are three basic characteristics of these pathways: 1) Small RNA biogenesis 2) Formation of RNA-induced silencing complexes.(RISCs). Protection against viruses []. An important aspect of RNA interference is its role in protecting organisms from some deleterious effects of a role for RNA interference was first found in plants, but has also been found in some animals.

Gene expression knockdown experiments []. RNA interference is now a widely used biology research technique that can be.

RNA interference, microRNAs and their relevance in development and cancer. STUDY. Flashcards. Learn. Write. Spell. Test. PLAY. Match. RNA interference (RNAi) is a mechanism that inhibits what. What are some RNAi targets. RNAi targets- RNA from viruses, and transposons, and development and genomic maintance.

1. RNA interference and its Applications By- Nitin Kumar Singh 2. Overview Introduction to RNAi Discovery Mechanism of Action Applications 3. INTRODUCTION RNA interference (RNAi) is a biological process in which RNA molecules inhibit gene expression, typically by causing the destruction of specific mRNA molecules 4.

This is the first comprehensive book on human/animal gene responses to RNA viral infections, including prevalent, emerging and re-emerging RNA viruses such as HIV, SARS-CoV, West Nile virus, influenza virus and many others.

Human gene responses are reviewed by leading virologists worldwide in the. Viral RNA silencing suppressors: Viral proteins/RNAs counteract RNA interference.

RNA silencing suppression phenomenon was first discovered in plant viruses. The plants infected with potato virus and cucumber mosaic virus exhibited suppression of Cited by: RNA Interference and Viruses: Current Innovations and Future by Miguel Angel k (United Kingdom): Caister Academic Press.

$ ix. RNA interference (or RNAi) is a natural process that cells use to silence the activity of specific genes, discovered by Andrew Fire and Craig Mello in These two American scientists were awarded the Nobel Prize in Physiology or Medicine for uncovering this fundamental mechanism of gene regulation.

Through RNA interference, or the process of temporarily barring gene expression, Monsanto scientists have been able to stop a pest from eating crops by spraying RNA that shuts down a gene the.

DNA and RNA Figure Structure of DNA. Except for some viruses, life’s genetic code is written in the DNA molecule (aka deoxyribonucleic acid). From the perspective of design, there is no human language that can match the simplicity and elegance of DNA.

But from the perspective of implementa-tion—how it is actually written and. The treatment of viral infections has relied on pre-emptive vaccination or use of a limited range of anti-viral drugs. However, the majority of viruses have no available drugs and treatment is merely supportive.

RNA interference (RNAi) offers the ability to directly and rapidly treat virus infections via the targeting of viral by: RNA interference is an important innate defence against viruses. Many viruses have a replication strategy that involves double-stranded RNA (dsRNA).

When such a virus infects a cell, it releases its RNA molecule. A protein complex called dicer sticks to it and chops the RNA into pieces. Then a biochemical pathway, called the RISC complex. A process called RNA interference breaks down the viral genetic material. The immune system produces special antibodies that can bind to viruses, making them non-infectious.

The body sends T cells Author: Peter Crosta.